Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

Helene Benveniste of Stony Brook University discusses the use of contrast-enhanced MRI to visualize the glymphatic system, a paravascular pathway that facilitates the clearance of waste and solutes from the cerebrospinal fluid and interstitial fluid of the brain. • Glymphatic pathway function can be measured using dynamic contrast-enhanced MRI. • Benveniste and colleagues used whole brain imaging to identify /confirm key features of the glymphatic pathway in rats. • Many degenerative brain diseases are ass