Expansion Microscopy of Brainbow Hippocampus

Brainbow-expressing mouse hippocampal brain circuitry, processed via the proExM form of expansion microscopy (ExM), which enables simple nanoscale resolution imaging on fast diffraction-limited microscopes. Video credits: Yosuke Bando, Young Gyu Yoon, Fei Chen, Dawen Cai, Ed Boyden. proExM is described in the paper Tillberg*, Chen*, et al., Nature Biotechnology (*, equal contributors), published July 4, 2016, from the Boyden lab at MIT ().