Developing a Complete In Silico Model of a Minimal Cell

This video illustrates the vision of the Center in developing a complete in silico model of a minimal cell. It was submitted as part of the Center’s collaborative application to the MacArthur Foundation’s 100&Change program. In collaboration with geneticists and microscopists, the Center will leverage its large-scale modeling software and expertise to completely describe a 400 nm cell on all time and length scales, helping to usher in a new era in biomedicine. Materials taken from Center work or collaborators, except for the Biochemical Pathways poster (created by Dr. Gerhard Michal; electronic version: © 2014 F. Hoffmann-La Roche Ltd).