Entamoeba histolytica: Life Cycle. In this 3D animation video, we show briefly the E. histolytica biological cycle. E. histolytica is a monogenetic parasite with a life cycle that it is completed in a single host (i.e., in humans). Three distinct morphological forms exist in its life cycle: Trophozoite, the Pre-cystic stage and the Cystic stage. Mode of infection: a matured quadrinucleate cyst of E. histolytica is the infective stage of the parasite. Transmission of E. histolytica from one person to another
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