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Circulating vitamin D level and mortality in prostate cancer patients: a dose–response meta-analysis
Results
Higher vitamin D level could reduce the risk of death among prostate cancer patients.
Association of circulating 25-hydroxyvitamin D level with prognosis of prostate cancer
We conducted a dose-response meta-analysis
Seven eligible cohort studies, n = 7, 808
The summary HR of prostate cancer-specific mortality
An increment of every 20 nmol/L in circulating
vitamin D,
(20 nmol/L = 8 ng/ml)
HR = , (P = )
Every 20 nmol/L increment in 25-hydroxyvitamin D level was associated with a 9% lower risk of,
all-cause mortality,
and prostate cancer-specific mortality.
Pooled HRs were stable and not obviously changed by any single study.
No evidence of publications bias was observed.
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