In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix. Gaps are inserted between the residues so that identical or similar characters are aligned in successive columns. Sequence alignments are also used for non-biological sequences, such as calculating the distance cost between strings in a natural language or in financial data.
Problems:
Mutant protein designated G189A. What does this reveal about the mutation?
The following three pieces of sequences originate from the same DNA string and have been found by sequencing. What is the sequence of the full DNA fragment?
A) 5’ AGCGTTAG 3’
B) 5’ CCGGTAAA 3’
C) 5’ AGCCGGTA 3’
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