Clinical Trial of mRNA Universal Influenza Vaccine Candidate Begins
Clinical trial, experimental universal influenza vaccine
National Institute of Allergy and Infectious Diseases’ (NIAID) Vaccine Research Center (VRC),
(part of National Institutes of Health)
Enrolling volunteers, Duke University, Durham, North Carolina
Phase 1 trial
H1ssF-3928 mRNA-LNP, for safety and ability to induce an immune response.
N = up to 50 healthy volunteers, (18 through 49)
Three groups of 10 participants each
10, 25 and 50 micrograms
After evaluation of the data to determine an optimum dosage,
an additional 10 to receive the optimum dosage
Study include a group, receive a current quadrivalent.
Comparison between “immunogenicity and safety”
Follow-up appointments for up
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