Interaction of eukaryotic CMG helicase with fork DNA

Baretić and Jenkyn-Bedford et al. describe high-resolution cryo-EM structure of the eukaryotic CMG helicase bound to replication fork DNA, suggesting a mechanism for strand separation. Check out the paper at: (20)30254-9 Baretić, D. , Jenkyn-Bedford, M., Aria, V., Cannone, G., Skehel, M., and Yeeles, . (2020). Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork. Mol Cell 78. For the best of Cell Press Videos, v