MIT Deep Learning in Genomics - Lecture 16 - Genetics 1: GWAS, Linkage, Fine-Mapping
Lecture 16 - Genetics 1: GWAS, Linkage, Fine-Mapping
MIT Lecture 16. Spring 2020
Course website:
Lecture 16 slides:
Lecture 16 outline: Deep Learning for Human Genetics and Disease
1. Human Genetics: Inheritance, Mendel, Fisher, SNPs, STRs, alleles
2. ‘Disease gene’ hunting: Common/rare alleles, Linkage vs. GWAS
3. Evolution/scaling of GWAS power: Sharing, inflection points
4. LD, Haplotypes, Co-inherit